91”ΔÎ

Updated: Sun, 10/06/2024 - 10:30

From Saturday, Oct. 5 through Monday, Oct. 7, the Downtown and Macdonald Campuses will be open only to 91”ΔΠstudents, employees and essential visitors. Many classes will be held online. Remote work required where possible. See Campus Public Safety website for details.

Du samedi 5 octobre au lundi 7 octobre, le campus du centre-ville et le campus Macdonald ne seront accessibles qu’aux Ă©tudiants et aux membres du personnel de l’UniversitĂ© 91”ΔÎ, ainsi qu’aux visiteurs essentiels. De nombreux cours auront lieu en ligne. Le personnel devra travailler Ă  distance, si possible. Voir le site Web de la Direction de la protection et de la prĂ©vention pour plus de dĂ©tails.

91”ΔÎ.CA / Ophthalmology & Visual Sciences / Research

91”ΔΠUveitis-Ocular Immunology Research and Clinical Unit

The Uveitis Research and Clinical Unit has been under the direction of the direction of Dr. Jean DeschĂȘnes, MD, FRCSC since 1986.The unit has attracted clinicians and researchers from around the world. Our mission of consultation, education and research has evolved into training many ocular immunologists, uveitis sub-specialists and researchers in Canada, Europe, Central, North and South America, and the Middle East.

Research Themes

Our research and clinical unit is involved in the understanding of the immunology of uveitis, medical and surgical therapy of uveitis including clinical trials, newer treatment like biologics agents, and monoclonal antibodies.

Research Activity

The eye is an immunologically privileged site, and our researches have shown specific molecular mechanisms for this process. Our research is aimed at understanding why intraocular tolerance fails in uveitis, what immune mechanisms initiate and drive the inflammatory response. and what can we do about it.

Laboratory

Our studies of uveitis are currently addressing the roles of a number of potentially harmful immune cell subsets. For many years, we have been collecting fluid from the front of the eye of patients with uveitis and comparing them to the cells we find in their peripheral blood, as well the blood of healthy individuals. 

We have published that the microenvironment in the eye suppresses the function of a key population of immune cells involved in the initiation of immune responses. We have also shown that the ocular fluids suppress the function of immuno-regulatory cells.

Clinical

We have several ongoing studies of novel approaches in the treatment of severe ocular inflammation and clinical trials for new therapies for intraocular inflammation and uveitis.

Useful links

Application for Fellowships (Research or Clinical)

Application for Medical Students

Email & Contact

jean.deschenes [at] mcgill.ca (91”ΔΠUveitis-Ocular Immunology Research and Clinical Unit)

jean.deschenes [at] mcgill.ca (Jean DeschĂȘnes, MD, FRCSC, Principal investigator)

delpechisabelle [at] hotmail.com (Isabelle Delpech, RN,)

Coordonatrice de recherches/Research coordinator
Centre acadĂ©mique de santĂ© de l’Ɠil de 91”ΔÎ/91”ΔΠAcademic Eye Centre
5252 Boul de Maisonneuve West, 4th floor
Montréal, Québec, H4A 3S5
Tel : (514)934-1934 ext :36814 (voice mail) or 40057
Fax : (514)843-1618
Pager  (514)406-1905

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